Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 3/20 | 0.53 |
| ▸ | FPR1 | P21462 | 1/20 | 0.53 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30466244 | 0.94 | MAP2K1 (0.51) | FPR2FPR1MAP2K1MAPTMEN1 | |
| SCHEMBL29009207 | 0.88 | USP2 (0.57) | MAP2K1MAPTMEN1KMT2AUSP2 | |
| SCHEMBL29009195 | 0.79 | SLC6A3 (0.45) | MMP1MMP13ALDH1A1 | |
| SCHEMBL29009179 | 0.79 | MMP1 (0.50) | MAPTMEN1KMT2AMMP1MMP13 | |
| SCHEMBL29009165 | 0.76 | KDM4E (0.50) | FPR2FPR1MAPTMEN1KMT2A | |
| SCHEMBL29009180 | 0.73 | ALDH1A1 (0.44) | HTTMMP1MMP13KDM4ELMNA | |
| SCHEMBL2171912 | 0.71 | FPR2 (0.48) | FPR2FPR1MAPTMAOAMAOB | |
| SCHEMBL1375586 | 0.71 | FPR2 (0.48) | FPR2FPR1MAPTMAOAMAOB | |
| SCHEMBL4921448 | 0.70 | RAB9A (0.81) | FPR2MAPTMEN1KMT2AMAOA | |
| SCHEMBL30466251 | 0.69 | CHRNA7 (0.48) | MAP2K1MAPTHTTUSP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217458-A | 2-carbonyl-5-phenylpyrrole compound, preparation method, application and derivative thereof, and pharmaceutical composition | 湖北民族大学 | 2023-06-06 | — | — | CN | disclosed |