Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK3 | P27361 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 5/20 | 0.42 |
| ▸ | FLT3 | P36888 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29009504 | 0.83 | PDPK1 (0.41) | PDPK1 | |
| SCHEMBL29009505 | 0.78 | MAPK1 (0.59) | MAPK3MAPK1PDPK1FLT3 | |
| SCHEMBL29009554 | 0.78 | PDPK1 (0.66) | PDPK1FLT3 | |
| SCHEMBL30382123 | 0.78 | PDPK1 (0.66) | PDPK1FLT3 | |
| SCHEMBL29009514 | 0.77 | — | — | |
| SCHEMBL30382435 | 0.74 | FGFR1 (0.62) | MAPK3MAPK1PDPK1FLT3 | |
| SCHEMBL29009498 | 0.74 | FGFR1 (0.62) | MAPK3MAPK1PDPK1FLT3 | |
| SCHEMBL29009559 | 0.72 | MAPK1 (0.47) | MAPK3MAPK1PDPK1 | |
| SCHEMBL29009533 | 0.71 | DRD2 (0.40) | PDPK1 | |
| SCHEMBL30382584 | 0.67 | CHEK1 (0.45) | MAPK3MAPK1PDPK1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217551-A | Substituted indazole or azaindazole compounds and application thereof | 河南中医药大学 | 2023-06-06 | — | — | CN | claimed |
| CN-116217551-A | Substituted indazole or azaindazole compounds and application thereof | 河南中医药大学 | 2023-06-06 | — | — | CN | disclosed |