Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29009675 | 0.81 | TP53 (0.41) | KMT2AMEN1NPC1RAB9ACYP3A4 | |
| SCHEMBL29837189 | 0.80 | L3MBTL1 (0.41) | KMT2AMEN1NPC1RAB9ATDP1 | |
| SCHEMBL29009676 | 0.78 | TP53 (0.49) | NPC1RAB9AALDH1A1 | |
| SCHEMBL1951077 | 0.74 | CYP1A2 (0.43) | KMT2AMEN1NPC1RAB9ATDP1 | |
| SCHEMBL9423795 | 0.73 | PYCR1 (0.39) | CYP3A4TRPM8SMN1; SMN2ALDH1A1 | |
| SCHEMBL29009673 | 0.73 | POLB (0.56) | KMT2AMEN1NPC1RAB9ACYP3A4 | |
| SCHEMBL16054223 | 0.72 | MEN1 (0.40) | KMT2AMEN1NPC1RAB9ATRPM8 | |
| SCHEMBL28948520 | 0.72 | TRPM8 (0.44) | KMT2AMEN1NPC1RAB9ATRPM8 | |
| SCHEMBL4585527 | 0.72 | PDPK1 (0.43) | KMT2AMEN1TAAR1ALDH1A1CA2 | |
| SCHEMBL29009677 | 0.71 | POLB (0.44) | KMT2AMEN1NPC1RAB9ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115010564-B | Preparation method of o-iodophenyl compound | 苏州大学 | 2024-03-19 | — | — | CN | disclosed |
| CN-115010564-A | Preparation method of o-iodophenyl compound | 苏州大学 | 2022-09-06 | — | — | CN | disclosed |