SCHEMBL29010069

SCHEMBL29010069

O=C(O)C(F)(C(F)F)C(F)(F)F.c1cc2ccc1-2

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.36
RXRA P19793 3/20 0.36
RXRB P28702 3/20 0.36
RXRG P48443 3/20 0.36
BCL2L1 Q07817 1/20 0.34
BAD Q92934 1/20 0.34
MAPT P10636 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
PTPN5 P54829 1/20 0.34
KIF11 P52732 5/20 0.33
PTGS2 P35354 1/20 0.31
CES1 P23141 1/20 0.31
FFAR1 O14842 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6898990 0.86 THRB (0.36) MAPTSMN1; SMN2
SCHEMBL29010127 0.84 KMO (0.40) RXRARXRBRXRGPTPN5PTGS2
Biphenyl SCHEMBL3647146 0.78 CYP2C9 (0.41) CYP2C9MAPTSMN1; SMN2PTPN5KIF11
SCHEMBL29009744 0.77 KIF11 (0.39) CYP2C9RXRARXRBRXRGBCL2L1
SCHEMBL29010058 0.74 CYP2C9 (0.36) CYP2C9RXRARXRBRXRGBCL2L1
Trifluoroacetic Acid SCHEMBL29009901 0.73 CYP2C9 (0.46) CYP2C9RXRARXRBRXRGBCL2L1
SCHEMBL29009861 0.72 THRB (0.44) CYP2C9RXRARXRBRXRGBCL2L1
SCHEMBL29010090 0.70 ALDH1A1 (0.41) CYP2C9RXRARXRBRXRGBCL2L1
SCHEMBL891799 0.68 PKM (0.30)
SCHEMBL2402177 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116209433-A Small molecule albumin binding agents 俄勒冈健康科学大学 2023-06-02 CN disclosed