Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29010240 | 0.85 | MAPT (0.44) | P2RX4NPC1L3MBTL1DHODHRAB9A | |
| SCHEMBL28710153 | 0.85 | SMN1; SMN2 (0.44) | P2RX4NPC1L3MBTL1RAB9AALDH1A1 | |
| SCHEMBL28694270 | 0.82 | FNTA (0.46) | ALKBH1EGLN1 | |
| SCHEMBL28696515 | 0.81 | RAB9A (0.44) | ATMNPC1RAB9AMAPTMAPK1 | |
| SCHEMBL28713751 | 0.79 | MAPKAPK2 (0.53) | ATML3MBTL1MAPKAPK2ALDH1A1KDR | |
| SCHEMBL16804931 | 0.78 | ALDH1A1 (0.49) | P2RX4NPC1L3MBTL1RAB9AALDH1A1 | |
| SCHEMBL29010232 | 0.77 | MGLL (0.41) | ALKBH1ALDH1A1MAPK1EGLN1 | |
| SCHEMBL28710156 | 0.77 | MGLL (0.45) | NPC1L3MBTL1RAB9AALKBH1MAPT | |
| SCHEMBL29010233 | 0.77 | GABRG2 (0.49) | P2RX4NPC1L3MBTL1RAB9AALDH1A1 | |
| SCHEMBL23481671 | 0.77 | ALDH1A1 (0.46) | P2RX4ATMNPC1L3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057646-B | Pyrazole derivative and application thereof in preparation of antitumor drugs | 常州大学 | 2023-05-02 | — | — | CN | disclosed |