SCHEMBL29013103

SCHEMBL29013103

CCOS(=O)(=O)c1ccc(C)c(-c2cc(Br)sc2Br)c1

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 2/20 0.33
PTGS2 P35354 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MT-CO1 P00395 1/20 0.33
MT-CO2 P00403 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PIK3CD O00329 2/20 0.32
PIK3CB P42338 2/20 0.32
PIK3CG P48736 2/20 0.32
CA2 P00918 1/20 0.31
PIK3C3 Q8NEB9 1/20 0.31
POLB P06746 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21834496 0.73 CYP1A2 (0.44) PTGS2CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL28428668 0.72 MEN1 (0.42) HSD17B10PIK3CDPIK3CBPIK3CGCA2
SCHEMBL28357540 0.72 ALDH1A1 (0.42) KDM4EHPGDCA2POLBHTT
SCHEMBL6262479 0.71 PTGS2 (0.44) PTGS1PTGS2HTT
SCHEMBL28968110 0.71 PTGS2 (0.42) PTGS1PTGS2CA2POLB
SCHEMBL9535051 0.70 PIK3CD (0.35) PIK3CDPIK3CBPIK3CGCA2PIK3C3
SCHEMBL28211544 0.69 KMT2A (0.38) PTGS1PTGS2HPGDTSHRHSD17B10
SCHEMBL5310644 0.68 TSHR (0.44) TSHRCA2POLBHTT
SCHEMBL6754204 0.68 LMNA (0.41) TSHRHTT
SCHEMBL28311125 0.68 ALDH1A1 (0.43) KDM4EHPGDTSHRHSD17B10HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116253864-A Application of conjugated polyelectrolyte material with amino acid groups in perovskite solar cell 南京工业大学 2023-06-13 CN disclosed