Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31250054 | 1.00 | LMNA (0.42) | LMNACES2CES1CYP2C19MAPK1 | |
| SCHEMBL324910 | 0.88 | LMNA (0.47) | LMNACES2CES1CYP2C19MAPK1 | |
| Benzene SCHEMBL28209572 | 0.88 | LMNA (0.47) | LMNACES2CES1CYP2C19MAPK1 | |
| Methoxymethane SCHEMBL11091635 | 0.83 | LMNA (0.42) | LMNACES2CES1CYP2C19MAPK1 | |
| Benzoin SCHEMBL28307199 | 0.83 | LMNA (0.58) | LMNACES2CES1CYP2C19MAPK1 | |
| Benzil SCHEMBL28225728 | 0.82 | LMNA (0.49) | LMNACES2CES1CYP2C19MAPK1 | |
| Ether SCHEMBL11098722 | 0.80 | LMNA (0.40) | LMNACES2CES1CYP2C19MAPK1 | |
| SCHEMBL2361001 | 0.79 | GABRA1 (0.46) | GABRA1GABRB2KDM4EMAPTMEN1 | |
| SCHEMBL474923 | 0.77 | AKR1C3 (0.44) | LMNAGABRA1GABRB2HPGDKDM4E | |
| SCHEMBL10340027 | 0.76 | GABRA1 (0.46) | LMNACYP2C19GABRA1GABRB2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116023333-B | Bio-based imidazole and preparation method and application thereof | 贵州大学 | 2024-10-11 | — | — | CN | disclosed |
| CN-116023333-A | Bio-based imidazole and preparation method and application thereof | 贵州大学 | 2023-04-28 | — | — | CN | disclosed |