Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.46 |
| ▸ | ALDH1A3 | P47895 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 7/20 | 0.39 |
| ▸ | RAB9A | P51151 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2901452 | 0.78 | NPC1 (0.47) | APPALDH1A3NPC1RAB9AALDH1A1 | |
| SCHEMBL2905527 | 0.78 | APP (0.43) | APPALDH1A3NPC1RAB9AALDH1A1 | |
| SCHEMBL2901138 | 0.71 | ALDH1A3 (0.75) | APPALDH1A3NPC1RAB9AALDH1A1 | |
| SCHEMBL1727234 | 0.71 | NPC1 (0.69) | APPALDH1A3NPC1RAB9AALDH1A1 | |
| SCHEMBL2905529 | 0.70 | APP (0.46) | APPALDH1A3NPC1RAB9AALDH1A1 | |
| SCHEMBL15177306 | 0.69 | APP (0.73) | APPALDH1A3NPC1RAB9AALDH1A1 | |
| SCHEMBL2810030 | 0.69 | APP (0.54) | APPALDH1A3NPC1RAB9AALDH1A1 | |
| SCHEMBL24320031 | 0.68 | NPC1 (0.74) | APPALDH1A3NPC1RAB9AALDH1A1 | |
| SCHEMBL2900566 | 0.68 | ALDH1A1 (0.40) | APPALDH1A3NPC1RAB9AALDH1A1 | |
| SCHEMBL2905532 | 0.68 | NPC1 (0.44) | APPALDH1A3NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2216050-A1 | UTILIZATION OF NOVEL COMPOUNDS WITH AMYLOID AFFINITY AND METHOD OF PRODUCING THE SAME | Nihon Medi-Physics Co., Ltd. (JP) | 2010-08-11 | — | — | EP | disclosed |