Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.46 |
| ▸ | ALDH1A3 | P47895 | 9/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | PKM | P14618 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2900569 | 0.89 | ALDH1A1 (0.42) | APPALDH1A3NPC1RAB9APKM | |
| SCHEMBL1727420 | 0.80 | NPC1 (0.50) | APPALDH1A3NPC1RAB9APKM | |
| SCHEMBL6491308 | 0.72 | ALDH1A3 (0.69) | APPALDH1A3NPC1RAB9APKM | |
| SCHEMBL2905527 | 0.72 | APP (0.43) | APPALDH1A3NPC1RAB9APKM | |
| SCHEMBL1727274 | 0.72 | ALDH1A3 (0.41) | APPALDH1A3NPC1RAB9APKM | |
| SCHEMBL2901138 | 0.71 | ALDH1A3 (0.75) | APPALDH1A3NPC1RAB9APKM | |
| SCHEMBL2901450 | 0.70 | APP (0.46) | APPALDH1A3NPC1RAB9APKM | |
| SCHEMBL15177306 | 0.69 | APP (0.73) | APPALDH1A3NPC1RAB9APKM | |
| SCHEMBL2431791 | 0.69 | APP (0.62) | APPALDH1A3NPC1RAB9APKM | |
| SCHEMBL2810030 | 0.69 | APP (0.54) | APPALDH1A3NPC1RAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2216050-A1 | UTILIZATION OF NOVEL COMPOUNDS WITH AMYLOID AFFINITY AND METHOD OF PRODUCING THE SAME | Nihon Medi-Physics Co., Ltd. (JP) | 2010-08-11 | — | — | EP | disclosed |