Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.39 |
| ▸ | CD44 | P16070 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 3/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8404445 | 0.82 | MEN1 (0.42) | ACHEBCHEGRIN1GRIN2AMEN1 | |
| SCHEMBL29015564 | 0.77 | ACHE (0.38) | ACHEMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL11627568 | 0.74 | ELANE (0.45) | ACHEALDH1A1PARP1ELANETSHR | |
| SCHEMBL24507538 | 0.69 | KDM4E (0.41) | CD44MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL10147922 | 0.69 | ACHE (0.46) | ACHECD44BCHEGRIN1GRIN2A | |
| SCHEMBL10250830 | 0.69 | NCF1 (0.56) | ACHEBCHEGRIN1GRIN2AMEN1 | |
| SCHEMBL1960424 | 0.67 | GPR3 (0.50) | ACHEMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL4507822 | 0.67 | NCF1 (0.44) | ACHECD44BCHEGRIN1GRIN2A | |
| SCHEMBL17278414 | 0.67 | CYP3A4 (0.41) | ACHECD44BCHEGRIN1GRIN2A | |
| SCHEMBL10200824 | 0.65 | ELANE (0.39) | ACHEBCHEGRIN1GRIN2APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947903-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116261564-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-06-13 | — | — | CN | disclosed |