SCHEMBL8404445

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29015346	0.82	ACHE (0.39)	MEN1ALDH1A1MAPTKMT2ATDP1
	SCHEMBL11627568	0.79	ELANE (0.45)	ALDH1A1ELANEPARP1ACHECYP1A2
	SCHEMBL436407	0.76	GPR3 (0.50)	MEN1ALDH1A1MAPTKMT2ATDP1
	SCHEMBL10200824	0.70	ELANE (0.39)	ELANEPARP1ACHEBCHEGRIN1
	SCHEMBL3884735	0.70	CYP1A2 (0.44)	MEN1ALDH1A1MAPTKMT2ACYP1A2
	SCHEMBL8404515	0.68	ELANE (0.50)	ELANEPARP1ACHE
	SCHEMBL8404451	0.68	ALDH1A1 (0.38)	MEN1ALDH1A1MAPTKMT2ATDP1
	SCHEMBL10200810	0.68	CYP1A2 (0.42)	MEN1ALDH1A1MAPTKMT2ATDP1
	SCHEMBL16626083	0.67	PRMT5 (0.49)	ALDH1A1MAPTTDP1ACHEBCHE
	SCHEMBL862362	0.65	ELANE (0.47)	ELANEPARP1ACHEBCHEGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.