Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LPL | P06858 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.31 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.31 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.31 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29017439 | 1.00 | TP53 (0.35) | TP53SMN1; SMN2FKBP1AOPRM1OPRD1 | |
| SCHEMBL22918343 | 0.88 | PRKAB2 (0.36) | TP53SMN1; SMN2FKBP1AOPRM1OPRD1 | |
| SCHEMBL29017358 | 0.83 | OPRM1 (0.45) | SMN1; SMN2OPRM1ALDH1A1LMNAP2RX7 | |
| SCHEMBL29017400 | 0.83 | OPRM1 (0.45) | SMN1; SMN2OPRM1ALDH1A1LMNAP2RX7 | |
| SCHEMBL10876937 | 0.81 | OPRM1 (0.40) | TP53SMN1; SMN2OPRM1OPRD1OPRK1 | |
| SCHEMBL29017386 | 0.80 | SLC6A3 (0.42) | OPRM1LMNAP2RX7 | |
| SCHEMBL29017376 | 0.80 | P2RX7 (0.47) | ALDH1A1P2RX7PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL29017384 | 0.80 | P2RX7 (0.40) | SMN1; SMN2OPRM1ALDH1A1LMNAP2RX7 | |
| SCHEMBL29017330 | 0.80 | SLC6A3 (0.42) | OPRM1LMNAP2RX7 | |
| SCHEMBL29017365 | 0.80 | P2RX7 (0.40) | SMN1; SMN2OPRM1ALDH1A1LMNAP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116240194-A | Limonene epoxy hydrolase mutant and catalytic synthesis of chiral oxygen/nitrogen-heterocyclic compound thereof | 中国科学院天津工业生物技术研究所 | 2023-06-09 | — | — | CN | claimed |
| CN-116240194-A | Limonene epoxy hydrolase mutant and catalytic synthesis of chiral oxygen/nitrogen-heterocyclic compound thereof | 中国科学院天津工业生物技术研究所 | 2023-06-09 | — | — | CN | disclosed |