Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ICMT | O60725 | 2/20 | 0.36 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.34 |
| ▸ | CHRNG | P07510 | 1/20 | 0.34 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | CHRND | Q07001 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29017400 | 1.00 | OPRM1 (0.45) | OPRM1L3MBTL1POLBLMNAP2RX7 | |
| SCHEMBL9839209 | 0.87 | LMNA (0.41) | OPRM1L3MBTL1POLBLMNAALDH1A1 | |
| SCHEMBL29017439 | 0.83 | TP53 (0.35) | OPRM1L3MBTL1LMNAP2RX7ALDH1A1 | |
| SCHEMBL29017353 | 0.83 | TP53 (0.35) | OPRM1L3MBTL1LMNAP2RX7ALDH1A1 | |
| SCHEMBL29017384 | 0.83 | P2RX7 (0.40) | OPRM1L3MBTL1POLBLMNAP2RX7 | |
| SCHEMBL29017365 | 0.83 | P2RX7 (0.40) | OPRM1L3MBTL1POLBLMNAP2RX7 | |
| SCHEMBL29017330 | 0.83 | SLC6A3 (0.42) | OPRM1LMNAP2RX7ICMTSLC6A2 | |
| SCHEMBL29017376 | 0.83 | P2RX7 (0.47) | P2RX7ALDH1A1SLC6A2SLC6A3 | |
| SCHEMBL29017380 | 0.83 | P2RX7 (0.47) | P2RX7ALDH1A1SLC6A2SLC6A3 | |
| SCHEMBL29017386 | 0.83 | SLC6A3 (0.42) | OPRM1LMNAP2RX7ICMTSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116240194-B | Limonene epoxy hydrolase mutant and catalytic synthesis of chiral oxygen/nitrogen-heterocyclic compound thereof | 中国科学院天津工业生物技术研究所 | 2024-11-12 | — | — | CN | claimed |
| CN-116240194-A | Limonene epoxy hydrolase mutant and catalytic synthesis of chiral oxygen/nitrogen-heterocyclic compound thereof | 中国科学院天津工业生物技术研究所 | 2023-06-09 | — | — | CN | claimed |
| CN-116240194-B | Limonene epoxy hydrolase mutant and catalytic synthesis of chiral oxygen/nitrogen-heterocyclic compound thereof | 中国科学院天津工业生物技术研究所 | 2024-11-12 | — | — | CN | disclosed |
| CN-116240194-A | Limonene epoxy hydrolase mutant and catalytic synthesis of chiral oxygen/nitrogen-heterocyclic compound thereof | 中国科学院天津工业生物技术研究所 | 2023-06-09 | — | — | CN | disclosed |