Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.61 |
| ▸ | HTR7 | P34969 | 2/20 | 0.61 |
| ▸ | HTR6 | P50406 | 2/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | ICMT | O60725 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29017367 | 0.90 | OPRM1 (0.50) | HTR1AHTR7HTR6OPRM1MEN1 | |
| SCHEMBL29017417 | 0.86 | OPRM1 (0.63) | HTR1AHTR7HTR6OPRM1MEN1 | |
| SCHEMBL29017371 | 0.85 | ICMT (0.47) | HTR1AHTR7HTR6OPRM1MEN1 | |
| SCHEMBL29017398 | 0.85 | MEN1 (0.49) | HTR1AHTR7HTR6OPRM1MEN1 | |
| SCHEMBL12541950 | 0.79 | OPRM1 (0.81) | HTR1AHTR7HTR6OPRM1L3MBTL1 | |
| SCHEMBL29017402 | 0.77 | ICMT (0.63) | ICMT | |
| SCHEMBL12542474 | 0.73 | OPRM1 (0.71) | HTR1AHTR7HTR6OPRM1ICMT | |
| SCHEMBL9973111 | 0.73 | MEN1 (0.74) | MEN1KMT2ATDP1SMN1; SMN2HTT | |
| SCHEMBL29017397 | 0.72 | ICMT (0.40) | OPRM1HTTMAOAICMT | |
| SCHEMBL29017373 | 0.72 | SIGMAR1 (0.41) | HTR1AHTR7HTR6OPRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116240194-B | Limonene epoxy hydrolase mutant and catalytic synthesis of chiral oxygen/nitrogen-heterocyclic compound thereof | 中国科学院天津工业生物技术研究所 | 2024-11-12 | — | — | CN | disclosed |
| CN-116240194-A | Limonene epoxy hydrolase mutant and catalytic synthesis of chiral oxygen/nitrogen-heterocyclic compound thereof | 中国科学院天津工业生物技术研究所 | 2023-06-09 | — | — | CN | disclosed |