Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 12/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29017373 | 0.79 | SIGMAR1 (0.41) | ICMTOPRM1 | |
| SCHEMBL29017367 | 0.78 | OPRM1 (0.50) | MAOAOPRM1 | |
| SCHEMBL29017487 | 0.76 | ICMT (0.38) | ICMTMAOAMAOBOPRM1HTT | |
| SCHEMBL29017415 | 0.74 | ICMT (0.63) | ICMT | |
| SCHEMBL29017382 | 0.72 | HTR1A (0.61) | ICMTMAOAOPRM1HTT | |
| SCHEMBL29017402 | 0.72 | ICMT (0.63) | ICMT | |
| SCHEMBL29017398 | 0.70 | MEN1 (0.49) | ICMTOPRM1HTT | |
| SCHEMBL5031526 | 0.70 | MAOA (0.41) | ICMTMAOAMAOBOPRM1SLC6A4 | |
| SCHEMBL29017417 | 0.70 | OPRM1 (0.63) | OPRM1 | |
| SCHEMBL29017405 | 0.70 | MAOB (0.50) | MAOAMAOBOPRM1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116240194-B | Limonene epoxy hydrolase mutant and catalytic synthesis of chiral oxygen/nitrogen-heterocyclic compound thereof | 中国科学院天津工业生物技术研究所 | 2024-11-12 | — | — | CN | disclosed |
| CN-116240194-A | Limonene epoxy hydrolase mutant and catalytic synthesis of chiral oxygen/nitrogen-heterocyclic compound thereof | 中国科学院天津工业生物技术研究所 | 2023-06-09 | — | — | CN | disclosed |