SCHEMBL29017402

SCHEMBL29017402

Cc1ccc(NCCC2(c3ccccc3)COC2)cc1

nearest known ligand 0.63

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ICMT O60725 19/20 0.63
MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29017415 0.89 ICMT (0.63) ICMT
SCHEMBL29017387 0.85 ICMT (0.62) ICMT
SCHEMBL29017382 0.77 HTR1A (0.61) ICMT
SCHEMBL18887016 0.72 ICMT (0.91) ICMT
SCHEMBL29017373 0.72 SIGMAR1 (0.41) ICMT
SCHEMBL29017397 0.72 ICMT (0.40) ICMT
SCHEMBL11530504 0.71 MAPT (0.81) ICMTMAPT
SCHEMBL29017367 0.71 OPRM1 (0.50) MAPT
SCHEMBL29017396 0.69 ACSS2 (0.39)
SCHEMBL29017487 0.69 ICMT (0.38) ICMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116240194-B Limonene epoxy hydrolase mutant and catalytic synthesis of chiral oxygen/nitrogen-heterocyclic compound thereof 中国科学院天津工业生物技术研究所 2024-11-12 CN disclosed
CN-116240194-A Limonene epoxy hydrolase mutant and catalytic synthesis of chiral oxygen/nitrogen-heterocyclic compound thereof 中国科学院天津工业生物技术研究所 2023-06-09 CN disclosed