4-Aminophenol

4-Aminophenol

SCHEMBL29019124

Nc1ccc(O)cc1.O=P(O)(O)O.O=S(O)(O)=S

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of 4-Aminophenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
CYP3A4 P08684 3/20 0.54
THRB P10828 3/20 0.54
CA6 P23280 2/20 0.54
CA14 Q9ULX7 2/20 0.54
ALOX15 P16050 2/20 0.54
CASP1 P29466 2/20 0.54
HIF1A Q16665 2/20 0.54
HSD17B10 Q99714 2/20 0.54
CA3 P07451 1/20 0.54
TSHR P16473 3/20 0.45
NT5E P21589 2/20 0.45
APP P05067 3/20 0.43
LMNA P02545 2/20 0.41
CA1 P00915 4/20 0.40
CA2 P00918 4/20 0.40
CA12 O43570 2/20 0.40
CA9 Q16790 2/20 0.40
ESR1 P03372 1/20 0.38
CYP19A1 P11511 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Aminophenol SCHEMBL28849641 0.87 CYP3A4 (0.72) ALDH1A1CYP3A4THRBCA6CA14
4-Aminophenol SCHEMBL78547 0.87 CYP3A4 (0.72) ALDH1A1CYP3A4THRBCA6CA14
4-Aminophenol SCHEMBL28175334 0.84 CYP3A4 (0.68) ALDH1A1CYP3A4THRBCA6CA14
4-Aminophenol SCHEMBL17436623 0.82 ALDH1A1 (0.72) ALDH1A1CYP3A4THRBCA6CA14
4-Aminophenol SCHEMBL1028523 0.82 ALDH1A1 (0.72) ALDH1A1CYP3A4THRBCA6CA14
4-Aminophenol SCHEMBL27327366 0.80 ALDH1A1 (0.68) ALDH1A1CYP3A4THRBCA6CA14
4-Aminophenol SCHEMBL29019125 0.79 ALDH1A1 (0.77) ALDH1A1CYP3A4THRBCA6CA14
Phosphoric Acid SCHEMBL6267680 0.76 MEN1 (0.57) ALDH1A1CYP3A4THRBCA6CA14
4-Aminophenol SCHEMBL22462461 0.75 ALDH1A1 (0.68) ALDH1A1CYP3A4THRBCA6CA14
Hydroquinone SCHEMBL9458925 0.74 TSHR (0.82) ALDH1A1CYP3A4THRBCA6CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116063974-A Polyurethane single-component adhesive for bonding redwood furniture and preparation method thereof 廊坊华宇创新科技有限公司 2023-05-05 CN disclosed