Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.33 |
| ▸ | CES1 | P23141 | 6/20 | 0.33 |
| ▸ | CES2 | O00748 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5344964 | 0.71 | MLYCD (0.37) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL3944363 | 0.71 | KDM6B (0.36) | — | |
| SCHEMBL7024069 | 0.71 | FAAH (0.39) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL28708698 | 0.70 | MLYCD (0.33) | FAAHCES1CES2MEN1CYP1A2 | |
| Ammonia Solution, Strong SCHEMBL28860981 | 0.69 | KDM6B (0.34) | — | |
| SCHEMBL31211614 | 0.68 | FAAH (0.36) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL28778447 | 0.68 | FAAH (0.44) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL3928482 | 0.68 | FAAH (0.41) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL7704491 | 0.66 | — | — | |
| SCHEMBL577250 | 0.66 | FAAH (0.33) | FAAHCES1CES2MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096710-A | 4-oxo-3, 4-dihydroquinazolinone compounds for the treatment of BRAF related diseases and disorders | 阿雷生物药品公司 | 2023-05-09 | — | — | CN | disclosed |