Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5643716 | 0.80 | HDAC6 (0.68) | ALDH1A1HPGDHSD17B1HSD17B2HDAC6 | |
| SCHEMBL29021866 | 0.79 | HTT (0.49) | ALDH1A1HPGDHSD17B1HSD17B2GAA | |
| SCHEMBL7259715 | 0.76 | APP (0.53) | ALDH1A1HPGDHSD17B1HSD17B2GAA | |
| SCHEMBL10913114 | 0.76 | IMPDH2 (0.48) | ALDH1A1GAAMAPTLMNAABL1 | |
| SCHEMBL6040630 | 0.76 | ERN1 (0.51) | ALDH1A1HPGDHSD17B1HSD17B2HDAC6 | |
| SCHEMBL29021811 | 0.75 | ALDH1A1 (0.46) | ALDH1A1HPGDHSD17B1HSD17B2HDAC6 | |
| SCHEMBL10915722 | 0.75 | APP (0.43) | ALDH1A1HPGDGAAMAPTSMN1; SMN2 | |
| SCHEMBL1235256 | 0.75 | LMNA (0.60) | ALDH1A1HPGDGAAMAPTSMN1; SMN2 | |
| SCHEMBL3918681 | 0.74 | HPGDS (0.59) | ALDH1A1HPGDHSD17B1HSD17B2HDAC6 | |
| SCHEMBL1598790 | 0.74 | HPGD (0.50) | ALDH1A1HPGDHSD17B1HSD17B2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143763-A | GAS41 targeting compound, GAS41 inhibitor and pharmaceutical composition and application thereof | 清华大学 | 2023-05-23 | — | — | CN | disclosed |