Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.38 |
| ▸ | FPR1 | P21462 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 3/20 | 0.36 |
| ▸ | MARS1 | P56192 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL336069 | 0.84 | ALDH1A1 (0.45) | FNTAFNTBFPR1NPSR1RXFP1 | |
| Quinoline SCHEMBL336068 | 0.84 | ALDH1A1 (0.45) | FNTAFNTBFPR1NPSR1RXFP1 | |
| Phenazine SCHEMBL28366290 | 0.83 | KIF11 (0.44) | FPR1KIF11 | |
| Quinazoline SCHEMBL1449265 | 0.78 | EGFR (0.59) | EGFRNPSR1RXFP1PIK3CDPIK3CA | |
| Phenanthrene SCHEMBL29137099 | 0.76 | KIF11 (0.45) | FNTAFNTBALDH1A1KIF11 | |
| Quinazoline SCHEMBL27468830 | 0.76 | EGFR (0.65) | EGFRNPSR1RXFP1PIK3CDPIK3CA | |
| Quinazoline SCHEMBL3128567 | 0.75 | EGFR (0.74) | EGFRPIK3CDPIK3CAALDH1A1SMN1; SMN2 | |
| Racemethionine SCHEMBL27686953 | 0.75 | BHMT (0.53) | NOS1 | |
| Racemethionine SCHEMBL14248767 | 0.74 | KIF11 (0.51) | KIF11 | |
| Cadaverine Tartrate SCHEMBL28557190 | 0.74 | EGFR (0.67) | EGFRNPSR1RXFP1PIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283799-A | Quinazoline methionine adenosyltransferase 2A inhibitors | 南京正大天晴制药有限公司 | 2023-06-23 | — | — | CN | disclosed |