Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.55 |
| ▸ | AXL | P30530 | 1/20 | 0.55 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.55 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 6/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochlorthiazide SCHEMBL27807287 | 0.82 | ACHE (0.41) | MEN1PSIP1AXLMKNK1MKNK2 | |
| Aniline SCHEMBL6204639 | 0.80 | TSHR (0.48) | MEN1MAOACYP3A4CYP19A1TSHR | |
| Biphenyl SCHEMBL2199525 | 0.76 | NOTUM (0.50) | MEN1CYP3A4CYP19A1TSHRPDPK1 | |
| M-Xylene SCHEMBL10710480 | 0.75 | ACHE (0.50) | MEN1CYP11B1CYP11B2ALDH1A1MAPT | |
| SCHEMBL29403794 | 0.74 | MAOA (0.83) | MEN1PSIP1AXLMKNK1MKNK2 | |
| SCHEMBL30500254 | 0.74 | MAOA (0.83) | MEN1PSIP1AXLMKNK1MKNK2 | |
| SCHEMBL251095 | 0.74 | MAOA (0.83) | MEN1PSIP1AXLMKNK1MKNK2 | |
| SCHEMBL583534 | 0.74 | CYP3A4 (0.70) | MEN1PSIP1AXLMKNK1MKNK2 | |
| Hydrochlorthiazide SCHEMBL28813777 | 0.74 | CYP3A4 (0.46) | MEN1CYP3A4TSHRATAD2ALDH1A1 | |
| Biphenyl SCHEMBL27870612 | 0.74 | NOTUM (0.48) | MEN1CYP3A4CYP19A1TSHRPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116284771-A | Fused heterocyclic hyperbranched conjugated polymer and preparation method and application thereof | 陕西师范大学 | 2023-06-23 | — | — | CN | claimed |