Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 5/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.32 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochlorthiazide SCHEMBL28813777 | 0.84 | CYP3A4 (0.46) | TSHRMAPTALDH1A1CYP2D6MEN1 | |
| Biphenyl SCHEMBL2199525 | 0.82 | NOTUM (0.50) | TSHRALDH1A1MEN1KMT2AMAPK1 | |
| Benzene SCHEMBL7782550 | 0.81 | TSHR (0.33) | TSHRTDP1 | |
| Hydrochlorthiazide SCHEMBL29022356 | 0.80 | MEN1 (0.55) | TSHRMAPTALDH1A1MEN1KMT2A | |
| Biphenyl SCHEMBL27870612 | 0.80 | NOTUM (0.48) | TSHRMAPTALDH1A1MEN1KMT2A | |
| Naphthalene SCHEMBL303703 | 0.79 | CYP2A6 (0.40) | ALDH1A1ALOX12CYP19A1 | |
| Hydrochlorthiazide SCHEMBL28187091 | 0.79 | ALDH1A1 (0.38) | TSHRMAPTALDH1A1CYP2D6MEN1 | |
| Fluorobenzene SCHEMBL10655817 | 0.78 | MAPK14 (0.32) | MAPTKDM4ENOTUM | |
| Toluene SCHEMBL10663158 | 0.78 | LMNA (0.48) | TSHRALDH1A1LMNASMN1; SMN2TDP1 | |
| Benzenethiol SCHEMBL11811993 | 0.78 | NOTUM (0.31) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1880942-B | Standard material for particle analyzer | SYSMEX CORP | 2012-11-07 | — | — | CN | disclosed |
| CN-1880942-A | Standard material for particle analyzer | SYSMEX CORP (JP) | 2006-12-20 | — | — | CN | disclosed |
| EP-1549278-A4 | M sb 3 /sb MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LTD (GB) | 2005-12-14 | — | — | EP | disclosed |
| CN-1226294-C | Fused heteroaromatic glucokinase activators | HOFFMANN LA ROCHE (CH) | 2005-11-09 | — | — | CN | disclosed |
| EP-1549278-A2 | M sb 3 /sb MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2005-07-06 | — | — | EP | disclosed |
| CN-1634900-A | Method for preparing 3-methyl-2-benzothiazolinone hydrazone and its hydrochloride | UNIV FUDAN (CN) | 2005-07-06 | — | — | CN | disclosed |
| CN-1476438-A | Fused heteroaromatic glucokinase activators | - | 2004-02-18 | — | — | CN | disclosed |
| WO-2004012684-A2 | M3MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2004-02-12 | — | — | WO | disclosed |
| CN-1009006-B | Thermosetting resin composition, and prepreg and laminated sheet material produced from the same | HITACHI LTD (JP) | 1990-08-01 | — | — | CN | disclosed |
| CN-1033065-A | Compositions of thermosetting resin reaches by its prepreg that makes and laminated plate material | HITACHI LTD (JP) | 1989-05-24 | — | — | CN | disclosed |