Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20337531 | 0.84 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1TDP1GLARECQL | |
| SCHEMBL24371527 | 0.78 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1GLAHSD17B10 | |
| SCHEMBL29023203 | 0.77 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL30409023 | 0.77 | KDM4E (0.38) | SMN1; SMN2HSD17B10HTT | |
| SCHEMBL3717877 | 0.77 | ALDH1A1 (0.40) | SMN1; SMN2ALDH1A1TDP1MAPTGLA | |
| SCHEMBL25746601 | 0.76 | TDP1 (0.39) | SMN1; SMN2ALDH1A1TDP1GLAALOX15 | |
| SCHEMBL2445606 | 0.74 | NPSR1 (0.46) | ALDH1A1HSD11B1MAPTCHRM1CYP3A4 | |
| SCHEMBL2707689 | 0.74 | HCN4 (0.40) | SMN1; SMN2ALDH1A1MAPTGLARECQL | |
| SCHEMBL28436716 | 0.69 | HSD11B1 (0.40) | HSD11B1CHRM1CYP3A4 | |
| SCHEMBL2451039 | 0.68 | NPSR1 (0.46) | ALDH1A1HSD11B1MAPTGLACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4232451-A1 | CFTR MODULATOR COMPOUNDS, COMPOSITIONS, AND USES THEREOF | Ildong Pharmaceutical Co., Ltd. (KR) | 2023-08-30 | — | — | EP | disclosed |
| CN-116348468-A | CFTR modulator compounds, compositions and uses thereof | 日东制药株式会社 | 2023-06-27 | — | — | CN | disclosed |
| WO-2022084741-A1 | CFTR MODULATOR COMPOUNDS, COMPOSITIONS, AND USES THEREOF | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-04-28 | — | — | WO | disclosed |