SCHEMBL290240

SCHEMBL290240

[CH2]CCCCCCCCCCCCC([CH2])CCCCCCCCCCC

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
DNM1 Q05193 2/20 0.40
TSHR P16473 1/20 0.40
THRB P10828 1/20 0.40
OPRM1 P35372 1/20 0.39
GPR84 Q9NQS5 3/20 0.37
FDPS P14324 3/20 0.37
SPHK1 Q9NYA1 1/20 0.37
FFAR1 O14842 1/20 0.37
MAPT P10636 1/20 0.35
LCK P06239 1/20 0.35
PPARD Q03181 1/20 0.35
ZDHHC20 Q5W0Z9 1/20 0.35
ZDHHC2 Q9UIJ5 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2139902 1.00 LMNA (0.41) LMNADNM1TSHRTHRBOPRM1
SCHEMBL2140719 1.00 LMNA (0.41) LMNADNM1TSHRTHRBOPRM1
SCHEMBL2137295 1.00 LMNA (0.41) LMNADNM1TSHRTHRBOPRM1
SCHEMBL9656413 1.00 LMNA (0.41) LMNADNM1TSHRTHRBOPRM1
SCHEMBL2139776 1.00 LMNA (0.41) LMNADNM1TSHRTHRBOPRM1
SCHEMBL1699698 1.00 LMNA (0.41) LMNADNM1TSHRTHRBOPRM1
SCHEMBL11285372 1.00 LMNA (0.41) LMNADNM1TSHRTHRBOPRM1
SCHEMBL3395197 1.00 LMNA (0.41) LMNADNM1TSHRTHRBOPRM1
SCHEMBL148380 0.95 DNM1 (0.40) LMNADNM1TSHRTHRBOPRM1
SCHEMBL19922801 0.95 DNM1 (0.40) LMNADNM1TSHRTHRBOPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3463260-A1 SYSTEM FOR DISPENSING A COSMETIC PRODUCT L'Oréal (FR) 2019-04-10 EP disclosed
WO-2018122014-A1 SUPERHYDROPHOBIC COSMETIC COMPOSITION IN AEROSOL FORM L'OREAL (FR) 2018-07-05 WO disclosed
WO-2018122187-A1 PICKERING EMULSION WITH AN IMPROVED SENSORY EFFECT L'OREAL (FR) 2018-07-05 WO disclosed
WO-2017207776-A1 SYSTEM FOR DISPENSING A COSMETIC PRODUCT L'OREAL (FR) 2017-12-07 WO disclosed
WO-2017207800-A1 SYSTEM FOR DISPENSING A COSMETIC PRODUCT L'OREAL (FR) 2017-12-07 WO disclosed
WO-2017207789-A1 SYSTEM FOR DISPENSING A COSMETIC PRODUCT L'OREAL (FR) 2017-12-07 WO disclosed
WO-2017103052-A1 COSMETIC COMPOSITION BASED ON WHITE PIGMENTS AND SPHERICAL TITANIUM DIOXIDE AGGREGATES L'OREAL (FR) 2017-06-22 WO disclosed
US-20160361242-A1 AQUEOUS COSMETIC COMPOSITION COMPRISING ALKYLCELLULOSE, NON-VOLATILE OILS, A HYDROPHILIC GELLING POLYMER AND A POLYOL L'OREAL (FR) 2016-12-15 US disclosed
WO-2016110543-A1 MASCARA WITH VOLATILE HYDROCARBON-BASED AND SILICONE SOLVENTS L'OREAL (FR) 2016-07-14 WO disclosed
WO-2016110535-A1 MASCARA COMPRISING SEMI-CRYSTALLINE POLYMER AND POLYBUTYLENE L'OREAL (FR) 2016-07-14 WO disclosed
WO-2010125543-A2 COSMETIC COMPOSITION COMPRISING A SURFACTANT WITH HLB GREATER THAN OR EQUAL TO 12 AND A COATED PIGMENT L'OREAL (FR) 2010-11-04 WO disclosed
EP-2219586-A2 METHOD FOR MAKING UP THE LIPS L'Oréal (FR) 2010-08-25 EP disclosed
WO-2010026538-A1 COSMETIC COMPOSITION CONTAINING A POLYMER COMPRISING A CARBOSILOXANE DENDRIMER UNIT L'OREAL (FR) 2010-03-11 WO disclosed
WO-2010026534-A1 COSMETIC COMPOSITIONS CONTAINING A POLYMER COMPRISING CARBOSILOXANE DENDRIMER UNITS L'OREAL (FR) 2010-03-11 WO disclosed
WO-2010010511-A2 ASSEMBLY AND COMPOSITION FOR MAKING UP AND/OR CARING FOR THE EYELASHES AND/OR THE EYEBROWS L'OREAL (FR) 2010-01-28 WO disclosed
WO-2010010295-A2 LONG-LASTING COLOURED COSMETIC COMPOSITION L'OREAL (FR) 2010-01-28 WO disclosed
WO-2010010510-A2 COSMETIC COMPOSITION WITH IMPROVED APPLICATION TIME L'OREAL (FR) 2010-01-28 WO disclosed
WO-2009092934-A1 COSMETIC COMPOSITION, IN PARTICULAR MAKEUP COMPOSITION FOR KERATINIC MATERIALS, HAVING IMPROVED COSMETIC PROPERTIES L'OREAL (FR) 2009-07-30 WO disclosed
WO-2009080963-A2 COSMETIC PROCESS USING A COMPOSITION COMPRISING A SILOXANE RESIN AND A NONIONIC SILICONE SURFACTANT L'OREAL (FR) 2009-07-02 WO disclosed
WO-2009081370-A2 METHOD FOR MAKING UP THE LIPS L'OREAL (FR) 2009-07-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160361242-A1 AQUEOUS COSMETIC COMPOSITION COMPRISING ALKYLCELLULOSE, NON-VOLATILE OILS, A HYDROPHILIC GELLING POLYMER AND A POLYOL LIPA, HACD3, LIPC LMNA 161/4885DNM1 3059/4885TSHR 3601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.