Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 11/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28869101 | 0.77 | CXCR3 (0.36) | OPRM1SLC6A2DRD2DRD3 | |
| SCHEMBL29967398 | 0.75 | SLC6A2 (0.38) | OPRM1SLC6A2DRD2DRD3 | |
| SCHEMBL29024045 | 0.67 | OPRM1 (0.33) | OPRM1SLC6A2DRD2DRD3HSD11B1 | |
| SCHEMBL28270989 | 0.67 | HSD11B1 (0.39) | OPRM1HSD11B1CHRM2CHRM4CHRM5 | |
| SCHEMBL29024060 | 0.65 | OPRM1 (0.34) | OPRM1SLC6A2DRD2DRD3HSD11B1 | |
| SCHEMBL28270921 | 0.64 | OPRM1 (0.35) | OPRM1SLC6A2CHRM2CHRM4CHRM5 | |
| SCHEMBL31114112 | 0.62 | OPRM1 (0.46) | OPRM1DRD2DRD3OPRD1OPRK1 | |
| SCHEMBL30790758 | 0.61 | OPRM1 (0.47) | OPRM1SLC6A2HSD11B1CHRM2CHRM4 | |
| SCHEMBL27381576 | 0.60 | CYP2D6 (0.40) | OPRM1SLC6A2OPRD1OPRK1KCNH2 | |
| SCHEMBL31114014 | 0.60 | OPRM1 (0.48) | OPRM1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115124520-A | Opioid receptor agonists and uses thereof | 四川海思科制药有限公司 | 2022-09-30 | — | — | CN | disclosed |