Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.46 |
| ▸ | YAP1 | P46937 | 3/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29024635 | 0.84 | TP53 (0.39) | PRMT5MAPTFAAHTP53LMNA | |
| SCHEMBL29024491 | 0.83 | LMNA (0.49) | GPR119MAPTMEN1KMT2ATDP1 | |
| SCHEMBL5447888 | 0.83 | CCR5 (0.50) | PRMT5GPR119GAAHPGDMAPT | |
| SCHEMBL29024487 | 0.82 | HRH1 (0.40) | PRMT5MAPTMEN1KMT2AFAAH | |
| SCHEMBL7589724 | 0.78 | MAPT (0.50) | PRMT5GPR119GAAHPGDMAPT | |
| SCHEMBL30478104 | 0.77 | FAAH (0.37) | MAPTMEN1KMT2AFAAHLMNA | |
| SCHEMBL29024637 | 0.77 | HTR2A (0.47) | — | |
| SCHEMBL7605901 | 0.72 | JAK2 (0.46) | GPR119GAATHRBSMN1; SMN2STS | |
| SCHEMBL29024482 | 0.72 | HTR2A (0.40) | — | |
| SCHEMBL5451783 | 0.71 | CCR5 (0.54) | GPR119GAATHRBSMN1; SMN2STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354925-A | Pyrazole derivatives and use thereof | 江苏恩华药业股份有限公司 | 2023-06-30 | — | — | CN | disclosed |