Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 12/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29024637 | 0.91 | HTR2A (0.47) | HTR2AHRH3 | |
| SCHEMBL29024487 | 0.89 | HRH1 (0.40) | LTA4HFAAHHTR2APRMT5MAPT | |
| SCHEMBL29024482 | 0.86 | HTR2A (0.40) | HTR2AHRH3 | |
| SCHEMBL29024486 | 0.84 | PRMT5 (0.46) | TP53FAAHPRMT5LMNAMAPT | |
| SCHEMBL29024642 | 0.84 | HTR2A (0.41) | TP53NPC1RAB9ALTA4HFAAH | |
| SCHEMBL30478104 | 0.84 | FAAH (0.37) | LTA4HFAAHHRH3LMNAMAPT | |
| SCHEMBL29024483 | 0.80 | LMNA (0.40) | TP53NPC1RAB9ALTA4HFAAH | |
| SCHEMBL30478094 | 0.77 | MEN1 (0.41) | NPC1RAB9ALTA4HFAAHHRH3 | |
| SCHEMBL29024485 | 0.77 | NPC1 (0.39) | TP53NPC1RAB9ALTA4HFAAH | |
| SCHEMBL29024488 | 0.77 | ABL1 (0.39) | FAAHHTR2APRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354925-A | Pyrazole derivatives and use thereof | 江苏恩华药业股份有限公司 | 2023-06-30 | — | — | CN | claimed |
| CN-116354925-A | Pyrazole derivatives and use thereof | 江苏恩华药业股份有限公司 | 2023-06-30 | — | — | CN | disclosed |