Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.39 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.39 |
| ▸ | MCTS1 | Q9ULC4 | 2/20 | 0.39 |
| ▸ | PDE6D | O43924 | 4/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.36 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.36 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29024635 | 0.89 | TP53 (0.39) | PRMT5LTA4HFAAHMAPTHTR2A | |
| SCHEMBL29024488 | 0.87 | ABL1 (0.39) | SLC16A3SLC16A1MCTS1PDE6DPRMT5 | |
| SCHEMBL29024639 | 0.85 | SLC16A3 (0.41) | HRH1SLC16A3SLC16A1MCTS1PDE6D | |
| SCHEMBL29024486 | 0.82 | PRMT5 (0.46) | SLC16A3SLC16A1MCTS1PRMT5FAAH | |
| SCHEMBL30478104 | 0.81 | FAAH (0.37) | HRH1SLC16A3SLC16A1MCTS1LTA4H | |
| SCHEMBL29024637 | 0.81 | HTR2A (0.47) | HTR2A | |
| SCHEMBL29024640 | 0.78 | HRH1 (0.39) | HRH1PDE6DPRMT5LTA4HFAAH | |
| SCHEMBL5764148 | 0.77 | CCR5 (0.48) | HRH1GABRA1GABRB2SMYD3KCNJ6 | |
| SCHEMBL30478094 | 0.76 | MEN1 (0.41) | SLC16A3SLC16A1MCTS1LTA4HFAAH | |
| SCHEMBL29024482 | 0.75 | HTR2A (0.40) | ABL1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354925-A | Pyrazole derivatives and use thereof | 江苏恩华药业股份有限公司 | 2023-06-30 | — | — | CN | claimed |
| CN-116354925-A | Pyrazole derivatives and use thereof | 江苏恩华药业股份有限公司 | 2023-06-30 | — | — | CN | disclosed |