Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 7/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.34 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.34 |
| ▸ | MCTS1 | Q9ULC4 | 2/20 | 0.34 |
| ▸ | PDE6D | O43924 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | GIPR | P48546 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | GPR4 | P46093 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29024482 | 0.88 | HTR2A (0.40) | ABL1HTR2AKCNH2HTR2C | |
| SCHEMBL29024487 | 0.87 | HRH1 (0.40) | ABL1HTR2ASLC16A3SLC16A1MCTS1 | |
| SCHEMBL29024489 | 0.83 | ABL1 (0.39) | ABL1HTR2ASLC16A3SLC16A1MCTS1 | |
| SCHEMBL30478116 | 0.80 | LMNA (0.36) | HTR2ASLC16A3SLC16A1MCTS1FAAH | |
| SCHEMBL30478103 | 0.77 | LTA4H (0.36) | FAAH | |
| SCHEMBL29024635 | 0.77 | TP53 (0.39) | HTR2APRMT5FAAH | |
| SCHEMBL29024637 | 0.76 | HTR2A (0.47) | HTR2AKCNH2HTR2C | |
| SCHEMBL29024639 | 0.74 | SLC16A3 (0.41) | ABL1HTR2ASLC16A3SLC16A1MCTS1 | |
| SCHEMBL29024481 | 0.71 | HTR2A (0.42) | ABL1HTR2AKCNH2HTR2C | |
| SCHEMBL30478119 | 0.69 | SLC16A3 (0.38) | SLC16A3SLC16A1MCTS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354925-A | Pyrazole derivatives and use thereof | 江苏恩华药业股份有限公司 | 2023-06-30 | — | — | CN | claimed |
| CN-116354925-A | Pyrazole derivatives and use thereof | 江苏恩华药业股份有限公司 | 2023-06-30 | — | — | CN | disclosed |