Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1707536 | 0.81 | ALOX5AP (0.37) | MAPTKDM4ECRHBPCRHR2ALDH1A1 | |
| SCHEMBL8947859 | 0.79 | PARP1 (0.35) | MAPTKDM4ECRHBPCRHR2ALDH1A1 | |
| SCHEMBL21684645 | 0.79 | ALDH1A1 (0.48) | MAPTKDM4ECRHBPCRHR2ALDH1A1 | |
| SCHEMBL6650609 | 0.78 | KDM4E (0.35) | MAPTKDM4ECRHBPCRHR2ALDH1A1 | |
| SCHEMBL6649047 | 0.78 | SCN9A (0.33) | MAPTKDM4ECRHBPCRHR2ALDH1A1 | |
| SCHEMBL6648850 | 0.78 | ALDH1A1 (0.32) | MAPTKDM4ECRHBPCRHR2ALDH1A1 | |
| SCHEMBL6649379 | 0.76 | L3MBTL1 (0.41) | MAPTKDM4EALDH1A1POLB | |
| SCHEMBL11084896 | 0.73 | PARP1 (0.35) | — | |
| SCHEMBL10434008 | 0.73 | PDE2A (0.30) | — | |
| SCHEMBL112835 | 0.73 | ALDH1A1 (0.43) | MAPTKDM4ECRHBPCRHR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-217511833-U | Reaction kettle for synthesizing 2, 3-difluorophenyl ethyl ether | 浙江解氏新材料股份有限公司 | 2022-09-30 | — | — | CN | disclosed |