Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8947859 | 0.85 | PARP1 (0.35) | KDM4EMAPTCRHBPCRHR2HTR2A | |
| SCHEMBL6649379 | 0.82 | L3MBTL1 (0.41) | KDM4EMAPTHTR2AHTR2CHTR2B | |
| SCHEMBL11084896 | 0.79 | PARP1 (0.35) | — | |
| SCHEMBL29025196 | 0.78 | MAPT (0.40) | KDM4EMAPTCRHBPCRHR2ALDH1A1 | |
| SCHEMBL10433956 | 0.77 | HTR2C (0.43) | HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL24180091 | 0.76 | FEN1 (0.41) | HTR2AHTR2CHTR2B | |
| SCHEMBL3819931 | 0.74 | LMNA (0.44) | HTR2AHTR2B | |
| SCHEMBL3819929 | 0.74 | LMNA (0.44) | HTR2AHTR2B | |
| SCHEMBL1707536 | 0.74 | ALOX5AP (0.37) | KDM4EMAPTCRHBPCRHR2HTR2A | |
| SCHEMBL29398924 | 0.74 | ALOX5AP (0.37) | KDM4EMAPTCRHBPCRHR2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990639-B1 | PROCESS FOR PRODUCING N-CYCLOPROPYLANILINES AND INTERMEDIATES USED THEREFOR | IHARA CHEMICAL IND CO (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6162944-A | Process for production of N-cyclopropylanilines and intermediates therefor | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2000-12-19 | — | — | US | disclosed |
| EP-0990639-A1 | PROCESS FOR PRODUCING N-CYCLOPROPYLANILINES AND INTERMEDIATES USED THEREFOR | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2000-04-05 | — | — | EP | disclosed |