Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29025848 | 1.00 | QDPR (0.41) | QDPRSMN1; SMN2KMT2AADAM10MMP2 | |
| SCHEMBL29025867 | 0.87 | KMT2A (0.35) | QDPRSMN1; SMN2KMT2AADAM10MMP2 | |
| SCHEMBL29025865 | 0.87 | KMT2A (0.35) | QDPRSMN1; SMN2KMT2AADAM10MMP2 | |
| SCHEMBL30478687 | 0.87 | NAMPT (0.45) | NAMPT | |
| SCHEMBL30478686 | 0.81 | TBK1 (0.33) | QDPRSMN1; SMN2KMT2ANAMPTALDH1A1 | |
| SCHEMBL30478691 | 0.81 | TBK1 (0.33) | QDPRSMN1; SMN2KMT2ANAMPTALDH1A1 | |
| SCHEMBL26697705 | 0.79 | ALDH1A1 (0.32) | SMN1; SMN2KMT2AALDH1A1TSHRHPGD | |
| SCHEMBL2470799 | 0.77 | QDPR (0.48) | QDPRSMN1; SMN2KMT2AADAM10MMP2 | |
| SCHEMBL16318395 | 0.74 | QDPR (0.45) | QDPRSMN1; SMN2KMT2AADAM10MMP2 | |
| SCHEMBL14191690 | 0.74 | GAA (0.44) | SMN1; SMN2KMT2AALDH1A1NPC1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109422755-B | Nitrogen-containing heterocyclic compound, preparation method, intermediate, composition and application | 上海医药集团股份有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-109422755-A | A kind of nitrogen-containing heterocycle compound, preparation method, intermediate, composition and application | 上海医药集团股份有限公司 | 2019-03-05 | — | — | CN | disclosed |