Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | QDPR | P09417 | 4/20 | 0.34 |
| ▸ | HTR1D | P28221 | 2/20 | 0.34 |
| ▸ | HTR1B | P28222 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29025865 | 1.00 | KMT2A (0.35) | KMT2ASMN1; SMN2QDPRHTR1DHTR1B | |
| SCHEMBL30478691 | 0.87 | TBK1 (0.33) | KMT2ASMN1; SMN2QDPRHTR1DHTR1B | |
| SCHEMBL30478686 | 0.87 | TBK1 (0.33) | KMT2ASMN1; SMN2QDPRHTR1DHTR1B | |
| SCHEMBL29025848 | 0.87 | QDPR (0.41) | KMT2ASMN1; SMN2QDPRALDH1A1MMP2 | |
| SCHEMBL29025852 | 0.87 | QDPR (0.41) | KMT2ASMN1; SMN2QDPRALDH1A1MMP2 | |
| SCHEMBL30478687 | 0.79 | NAMPT (0.45) | NAMPT | |
| SCHEMBL4014542 | 0.72 | GAA (0.44) | KMT2ASMN1; SMN2ALDH1A1TSHRMAPK1 | |
| SCHEMBL4014545 | 0.72 | GAA (0.44) | KMT2ASMN1; SMN2ALDH1A1TSHRMAPK1 | |
| SCHEMBL14191690 | 0.72 | GAA (0.44) | KMT2ASMN1; SMN2ALDH1A1TSHRMAPK1 | |
| SCHEMBL20605293 | 0.70 | ALDH1A1 (0.40) | KMT2ASMN1; SMN2ALDH1A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109422755-B | Nitrogen-containing heterocyclic compound, preparation method, intermediate, composition and application | 上海医药集团股份有限公司 | 2023-07-04 | — | — | CN | disclosed |