Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7286421 | 0.88 | MAOB (0.51) | MAOBBCHEMEN1KMT2ALMNA | |
| SCHEMBL29026273 | 0.85 | MEN1 (0.48) | MAOBMEN1KMT2AAPPLMNA | |
| SCHEMBL29026332 | 0.85 | BCHE (0.47) | MAOBBCHEAPPLMNACYP1A2 | |
| SCHEMBL6201495 | 0.84 | MAOB (0.51) | MAOBBCHEMEN1KMT2AABCB1 | |
| SCHEMBL3070157 | 0.82 | LMNA (0.53) | MAOBBCHELTA4HLMNACYP1A2 | |
| SCHEMBL8845456 | 0.81 | LTA4H (0.63) | MAOBBCHEMEN1KMT2AABCB1 | |
| SCHEMBL791985 | 0.79 | MAOB (0.69) | MAOBBCHEMEN1KMT2AABCB1 | |
| SCHEMBL29026266 | 0.78 | RXRA (0.48) | MAOBCYP1A2CYP2C19RAB9ANPC1 | |
| SCHEMBL29026306 | 0.77 | HPGD (0.43) | MAOBBCHEMEN1KMT2ALMNA | |
| SCHEMBL11844522 | 0.76 | LTA4H (0.67) | MAOBBCHEMEN1KMT2ALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116348450-A | Compounds, compositions and methods for histone lysine demethylase inhibition | 菲布罗根有限公司 | 2023-06-27 | — | — | CN | disclosed |