SCHEMBL3070157

SCHEMBL3070157

[c]1cc(OCc2ccccc2)ccc1OCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.53
CYP1A2 P05177 1/20 0.53
PTGS1 P23219 1/20 0.53
SLC6A2 P23975 1/20 0.53
CYP2C19 P33261 1/20 0.53
PTGS2 P35354 1/20 0.53
SLC6A3 Q01959 1/20 0.53
HIF1A Q16665 1/20 0.53
HDAC6 Q9UBN7 1/20 0.53
MAOB P27338 6/20 0.52
MAOA P21397 3/20 0.52
GAA P10253 1/20 0.52
MAPT P10636 1/20 0.52
RAB9A P51151 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
ALOX5 P09917 1/20 0.50
GSTP1 P09211 1/20 0.49
BCHE P06276 1/20 0.49
NR4A1 P22736 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7286421 0.88 MAOB (0.51) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL6201495 0.88 MAOB (0.51) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL27733165 0.85 LTA4H (0.50) LMNARAB9ASMN1; SMN2L3MBTL1LTA4H
SCHEMBL29026273 0.82 MEN1 (0.48) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL29026332 0.82 BCHE (0.47) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL29026282 0.82 MAOB (0.50) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL10414960 0.81 LMNA (0.53) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL29026306 0.80 HPGD (0.43) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL511881 0.80 BCHE (0.40) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL2321158 0.80 LMNA (0.52) LMNACYP1A2PTGS1SLC6A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0014887-B1 SPIRO DERIVATIVES OF 3-(3,5-DIHALOPHENYL)-OXAZOLIDINE-2-THION-4-ONES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES BAYER AG (DE) 1981-10-14 EP claimed
EP-2760947-B1 INKJET INK COMPOSITION AND INKJET RECORDING METHOD FUJIFILM CORP (JP) 2015-11-04 EP disclosed
EP-2239057-B1 Asymmetric catalyst and process for preparing optically active alcohols using the same KANTO KAGAKU (JP) 2015-06-03 EP disclosed
US-8939543-B2 Inkjet ink composition and inkjet recording method FUJIFILM CORPORATION (JP) 2015-01-27 US disclosed
EP-2760947-A2 INKJET INK COMPOSITION AND INKJET RECORDING METHOD FUJIFILM Corporation (JP) 2014-08-06 EP disclosed
US-20140204149-A1 INKJET INK COMPOSITION AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2014-07-24 US disclosed
WO-2013046679-A2 INKJET INK COMPOSITION AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2013-04-04 WO disclosed
US-8232420-B2 Asymmetric catalyst and process for preparing optically active alcohols using the same KANTO KAGAKU KABUSHIKI KAISHA (JP) 2012-07-31 US disclosed
US-20120184693-A1 ETHYLENE POLYMER PREPARATION METHOD SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-19 US disclosed
US-20100261924-A1 ASYMMETRIC CATALYST AND PROCESS FOR PREPARING OPTICALLY ACTIVE ALCOHOLS USING THE SAME KANTO KAGAKU KABUSHIKI KAISHA (JP) 2010-10-14 US disclosed
US-4344894-A TRANSITION METAL COMPLEX OF SCHIFF BASES AS CATALYSTS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1982-08-17 US disclosed
US-4343935-A CATALYSTS FOR CYCLOPROPANIZATION OF OLEFINS BY DIAZOACETATES IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1982-08-10 US disclosed
EP-0014887-B1 SPIRO DERIVATIVES OF 3-(3,5-DIHALOPHENYL)-OXAZOLIDINE-2-THION-4-ONES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES BAYER AG (DE) 1981-10-14 EP disclosed
US-4288387-A REACTION OF A HALOGENOPENTENE OR HEXENE WITH A DIAZOACETIC ESTER IN THE PRESENCE OF CATALYST WHICH IS METALLIC COPPER, A COPPER SALT, A RHODIUM SALT, OR A TRANSITION METAL COMPLEX OF A CHIRAL SCHIFF BASE IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-09-08 US disclosed
EP-0024795-A1 Chiral compounds and process for their preparation IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-03-11 EP disclosed
EP-0024796-A1 Chiral amino-alcohol complexes and process for their preparation IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-03-11 EP disclosed
EP-0023075-A1 Process for the preparation of cyclopropane carboxylic acid esters IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-01-28 EP disclosed
EP-0022608-A1 Process for the preparation of cyclopropane carboxylic acid esters IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-01-21 EP disclosed
US-4029690-A WITH 2,5-DIMETHYL-2,4-HEXADIENE AND AN ALKYL DIAZOACETATE WITH A COPPER COMPLEX CATALYST SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-06-14 US disclosed
US-4029683-A WITH A SCHIFF BASE, CHRYSANTHEMATE SYNTHESIS CATALYST SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100261924-A1 ASYMMETRIC CATALYST AND PROCESS FOR PREPARING OPTICALLY ACTIVE ALCOHOLS USING THE SAME ADH1A, ADH1C, ADH5 LMNA 2545/4885CYP1A2 234/4885PTGS1 2258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.