Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29026332 | 0.83 | BCHE (0.47) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL3070157 | 0.80 | LMNA (0.53) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL29026273 | 0.80 | MEN1 (0.48) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL29026266 | 0.78 | RXRA (0.48) | RXRARXRBCYP1A2CYP2C19RAB9A | |
| SCHEMBL29026282 | 0.77 | MAOB (0.50) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL7286421 | 0.76 | MAOB (0.51) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL2321158 | 0.76 | LMNA (0.52) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL8672333 | 0.73 | L3MBTL1 (0.60) | HPGDRXRARXRBHTR1AADRA1D | |
| SCHEMBL3047774 | 0.73 | HPGD (0.69) | HPGDRXRARXRBHTR1AADRA1D | |
| SCHEMBL6201495 | 0.70 | MAOB (0.51) | HTR1ALMNACYP1A2PTGS1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116348450-A | Compounds, compositions and methods for histone lysine demethylase inhibition | 菲布罗根有限公司 | 2023-06-27 | — | — | CN | disclosed |