SCHEMBL29026477

SCHEMBL29026477

COc1ccc(Cc2ccccc2C(=O)SC)cc1

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.49
HPGD P15428 2/20 0.48
USP2 O75604 1/20 0.48
TP53 P04637 1/20 0.48
SAE1 Q9UBE0 1/20 0.48
UBA2 Q9UBT2 1/20 0.48
KMT2A Q03164 3/20 0.46
TSHR P16473 1/20 0.45
ALDH1A1 P00352 5/20 0.45
MEN1 O00255 1/20 0.45
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
MAOB P27338 1/20 0.43
GLA P06280 1/20 0.43
ATM Q13315 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7020789 0.84 TSHR (0.53) TSHRALDH1A1L3MBTL1TDP1
SCHEMBL29026480 0.83 TSHR (0.41) HPGDKMT2ATSHRALDH1A1MEN1
SCHEMBL2839519 0.83 TSHR (0.66) LTA4HUSP2TP53SAE1UBA2
SCHEMBL29026489 0.83 KEAP1 (0.51) TSHRALDH1A1L3MBTL1TDP1
SCHEMBL21357059 0.82 LTA4H (0.51) LTA4HUSP2TP53SAE1UBA2
SCHEMBL27641694 0.82 LTA4H (0.51) LTA4HHPGDUSP2TP53SAE1
SCHEMBL27557414 0.81 ALDH1A1 (0.55) LTA4HHPGDUSP2TP53KMT2A
SCHEMBL9726125 0.80 LTA4H (0.56) LTA4HUSP2TP53SAE1UBA2
SCHEMBL28394767 0.79 HDAC3 (0.53) LTA4HHPGDUSP2TP53SAE1
SCHEMBL26103652 0.79 CTSD (0.54) LTA4HHPGDUSP2TP53SAE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118749013-A Resin composition, cured product, electronic component, and display device 东丽株式会社 2024-10-08 CN disclosed
CN-118369596-A Resin composition for lens, cured product for lens, and lens 三井化学株式会社 2024-07-19 CN disclosed
CN-118284274-A Charge-transporting varnish 日产化学株式会社 2024-07-02 CN disclosed
CN-112470551-B Sealing agent for organic electroluminescent display element 电化株式会社 2024-05-14 CN disclosed
CN-113227159-B Composition and method for producing the same 电化株式会社 2024-04-19 CN disclosed
CN-117586478-A Curable composition, cured product thereof, and wafer level lens 株式会社大赛璐 2024-02-23 CN disclosed
CN-117546089-A Photosensitive resin composition, photosensitive resin coating, photosensitive dry film, and pattern forming method 信越化学工业株式会社 2024-02-09 CN disclosed
CN-117510794-A Composition and method for producing the same 电化株式会社 2024-02-06 CN disclosed
CN-113272383-B Composition and method for producing the same 电化株式会社 2023-11-17 CN disclosed
CN-116997858-A Negative photosensitive resin composition, negative photosensitive resin composition film, cured product, method for producing cured product, hollow structure, and electronic component 东丽株式会社 2023-11-03 CN disclosed
CN-113227169-B Sealant, cured body, organic electroluminescent display device, and method for manufacturing device 电化株式会社 2023-10-31 CN disclosed
CN-116710846-A Photosensitive resin composition, photosensitive resin coating film, photosensitive dry film, and pattern forming method 信越化学工业株式会社 2023-09-05 CN disclosed
CN-116249722-A Composition, cured product, and organic EL display device 电化株式会社 2023-06-09 CN disclosed
CN-116194508-A Sealant, cured body, organic electroluminescent display device, and method for manufacturing organic electroluminescent display device 电化株式会社 2023-05-30 CN disclosed