SCHEMBL29026489

SCHEMBL29026489

CSC(=O)c1ccccc1Cc1ccc(O)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.51
TSHR P16473 2/20 0.49
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
CYP19A1 P11511 1/20 0.41
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
GFER P55789 1/20 0.40
MAPT P10636 2/20 0.40
RECQL P46063 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
TBXA2R P21731 1/20 0.40
PTGER3 P43115 1/20 0.40
PTGER2 P43116 1/20 0.40
PTGDR Q13258 1/20 0.40
FNTA P49354 1/20 0.40
FNTB P49356 1/20 0.40
LIG1 P18858 1/20 0.39
EGFR P00533 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7020789 0.88 TSHR (0.53) TSHRCA1CA2CA9MAPT
SCHEMBL29026477 0.83 LTA4H (0.49) TSHRL3MBTL1ALDH1A1TDP1
SCHEMBL29026504 0.80 TBXA2R (0.50) TSHRTBXA2RPTGER3PTGER2PTGDR
SCHEMBL2292722 0.80 TSHR (0.74) KEAP1TSHRESR1ESR2CA1
SCHEMBL29026480 0.79 TSHR (0.41) TSHRCA1CA2CA9MAPT
SCHEMBL5723934 0.78 KEAP1 (0.56) KEAP1TSHRESR1ESR2CYP19A1
SCHEMBL28463447 0.78 KEAP1 (0.56) KEAP1TSHRESR1ESR2CYP19A1
SCHEMBL19843863 0.77 ALDH1A1 (0.54) KEAP1TSHRCA1CA2CA9
SCHEMBL10174587 0.77 CLCN2 (0.42) TSHRMAPTALDH1A1
SCHEMBL11035548 0.77 TSHR (0.60) KEAP1TSHRCYP19A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118749013-A Resin composition, cured product, electronic component, and display device 东丽株式会社 2024-10-08 CN disclosed
CN-118369596-A Resin composition for lens, cured product for lens, and lens 三井化学株式会社 2024-07-19 CN disclosed
CN-118284274-A Charge-transporting varnish 日产化学株式会社 2024-07-02 CN disclosed
CN-112470551-B Sealing agent for organic electroluminescent display element 电化株式会社 2024-05-14 CN disclosed
CN-113227159-B Composition and method for producing the same 电化株式会社 2024-04-19 CN disclosed
CN-117586478-A Curable composition, cured product thereof, and wafer level lens 株式会社大赛璐 2024-02-23 CN disclosed
CN-117546089-A Photosensitive resin composition, photosensitive resin coating, photosensitive dry film, and pattern forming method 信越化学工业株式会社 2024-02-09 CN disclosed
CN-117510794-A Composition and method for producing the same 电化株式会社 2024-02-06 CN disclosed
CN-113272383-B Composition and method for producing the same 电化株式会社 2023-11-17 CN disclosed
CN-116997858-A Negative photosensitive resin composition, negative photosensitive resin composition film, cured product, method for producing cured product, hollow structure, and electronic component 东丽株式会社 2023-11-03 CN disclosed
CN-113227169-B Sealant, cured body, organic electroluminescent display device, and method for manufacturing device 电化株式会社 2023-10-31 CN disclosed
CN-116710846-A Photosensitive resin composition, photosensitive resin coating film, photosensitive dry film, and pattern forming method 信越化学工业株式会社 2023-09-05 CN disclosed
CN-116249722-A Composition, cured product, and organic EL display device 电化株式会社 2023-06-09 CN disclosed
CN-116194508-A Sealant, cured body, organic electroluminescent display device, and method for manufacturing organic electroluminescent display device 电化株式会社 2023-05-30 CN disclosed