Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3276135 | 0.84 | MAOA (0.54) | MAOAMAPTSMN1; SMN2ALDH1A1CYP1A2 | |
| Aminocaproic Acid SCHEMBL29028429 | 0.69 | MEN1 (0.41) | MAOAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL16828137 | 0.68 | ALDH1A1 (0.45) | MAOAMAPTSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL358014 | 0.66 | ALDH1A1 (0.61) | MAPTSMN1; SMN2MITFHTTALDH1A1 | |
| SCHEMBL31290996 | 0.66 | GPR35 (0.52) | MAOAMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL19606518 | 0.66 | TYMS (0.47) | MAOAMAPTSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL13239012 | 0.64 | HTR1A (0.53) | — | |
| SCHEMBL30992343 | 0.64 | HTR1A (0.53) | — | |
| SCHEMBL28710049 | 0.64 | LMNA (0.38) | MAOAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6445623 | 0.64 | ATM (0.43) | MAOASMN1; SMN2ALDH1A1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106456454-B | Disintegrable core/shell silica particles for encapsulating and releasing biologically active macromolecules | 斯特拉斯堡大学 | 2021-02-02 | — | — | CN | disclosed |