SCHEMBL2902897

SCHEMBL2902897

Clc1cccc(Oc2cc[c]cc2)n1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.47
F2 P00734 3/20 0.39
F10 P00742 3/20 0.39
PRSS1 P07477 1/20 0.39
PRSS2 P07478 1/20 0.39
PRSS3 P35030 1/20 0.39
ST14 Q9Y5Y6 1/20 0.39
P2RX3 P56373 8/20 0.38
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36
CYP3A4 P08684 1/20 0.34
TSHR P16473 1/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
PTGS2 P35354 1/20 0.34
HTT P42858 1/20 0.33
BACE1 P56817 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9491757 0.86 L3MBTL1 (0.53) L3MBTL1F2F10PRSS1PRSS2
SCHEMBL9492874 0.84 L3MBTL1 (0.51) L3MBTL1F2F10PRSS1PRSS2
SCHEMBL2144034 0.82 L3MBTL1 (0.54) L3MBTL1F2F10PRSS1PRSS2
SCHEMBL9496948 0.81 L3MBTL1 (0.49) L3MBTL1F2F10PRSS1PRSS2
SCHEMBL958339 0.81 MEN1 (0.51) L3MBTL1F2F10PRSS1PRSS2
SCHEMBL9490952 0.79 L3MBTL1 (0.62) L3MBTL1F2F10PRSS1PRSS2
SCHEMBL9271136 0.78 L3MBTL1 (0.50) L3MBTL1F2F10PRSS1PRSS2
SCHEMBL693523 0.78 F2 (0.39) F2F10PRSS1PRSS2PRSS3
SCHEMBL16695498 0.78 MEN1 (0.51) L3MBTL1F2F10PRSS1PRSS2
SCHEMBL6772010 0.78 L3MBTL1 (0.54) L3MBTL1F2F10PRSS1PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100305124-A1 Acylated Aminopyridine and Aminopyridazine Insecticides BAYER CROPSCIENCE AG (DE) 2010-12-02 US disclosed
EP-2236505-A1 Acylated aminopyridines and pyridazines as insecticides Bayer CropScience AG (DE) 2010-10-06 EP disclosed
US-4063928-A Composition and method of controlling undesired plant growth with substituted pyridinyloxy(thio)phenyl -acetamides, -ureas and urea derivatives THE DOW CHEMICAL COMPANY (US) 1977-12-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100305124-A1 Acylated Aminopyridine and Aminopyridazine Insecticides AAAS, DDT, QDPR L3MBTL1 1263/4885F2 472/4885F10 897/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.