Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 3/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.30 |
| ▸ | USP2 | O75604 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29029204 | 1.00 | ADRA2A (0.35) | ADRA2AADRA2BADRA2CCDK5CDK5R1 | |
| SCHEMBL30491128 | 1.00 | ADRA2A (0.35) | ADRA2AADRA2BADRA2CCDK5CDK5R1 | |
| SCHEMBL29029193 | 0.70 | PDGFRB (0.46) | MAPTKDM4ECYP3A4ALOX15ALDH1A1 | |
| SCHEMBL29029194 | 0.70 | PDGFRB (0.46) | MAPTKDM4ECYP3A4ALOX15ALDH1A1 | |
| SCHEMBL30491145 | 0.70 | PDGFRB (0.46) | MAPTKDM4ECYP3A4ALOX15ALDH1A1 | |
| SCHEMBL246438 | 0.70 | KDM4E (0.53) | MAPTKDM4ECYP3A4ALOX15TP53 | |
| SCHEMBL1615698 | 0.70 | ADRA2A (0.44) | ADRA2AADRA2BADRA2CCDK5CDK5R1 | |
| SCHEMBL23349333 | 0.68 | ADRA2A (0.42) | ADRA2AADRA2BADRA2CCDK5CDK5R1 | |
| SCHEMBL17177529 | 0.68 | ADRA2A (0.42) | ADRA2AADRA2BADRA2CCDK5CDK5R1 | |
| SCHEMBL28639731 | 0.68 | KDM4E (0.52) | MAPTKDM4ECYP3A4ALOX15TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260116856-A1 | METHOD FOR PREPARING META-(CHIRAL ALLYL)-SUBSTITUTED PYRIDINE COMPOUND | NANKAI UNIVERSITY (CN) | 2026-04-30 | — | — | US | disclosed |
| WO-2024216732-A1 | METHOD FOR PREPARING PYRIDINE COMPOUND WITH META POSITION THEREOF SUBSTITUTED BY CHIRAL ALLYL | 南开大学 | 2024-10-24 | — | — | WO | disclosed |
| CN-116396211-A | Method for preparing meta-chiral allyl substituted pyridine compound | 南开大学 | 2023-07-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260116856-A1 | METHOD FOR PREPARING META-(CHIRAL ALLYL)-SUBSTITUTED PYRIDINE COMPOUND | GAPVD1, TDO2, NOD1 | ADRA2A 168/4885ADRA2B 485/4885ADRA2C 289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.