Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29065067 | 0.77 | POLB (0.42) | EPHX2TSHRL3MBTL1PPARGALDH1A1 | |
| SCHEMBL30302005 | 0.69 | EPHX2 (0.44) | EPHX2L3MBTL1PPARGALDH1A1MEN1 | |
| SCHEMBL25392489 | 0.69 | MEN1 (0.38) | EPHX2L3MBTL1PPARGALDH1A1MEN1 | |
| SCHEMBL25392488 | 0.69 | MEN1 (0.38) | EPHX2L3MBTL1PPARGALDH1A1MEN1 | |
| SCHEMBL25393644 | 0.69 | MEN1 (0.38) | EPHX2L3MBTL1PPARGALDH1A1MEN1 | |
| SCHEMBL29229 | 0.68 | LMNA (0.44) | EPHX2L3MBTL1PPARGALDH1A1MEN1 | |
| SCHEMBL31328905 | 0.68 | PKM (0.48) | EPHX2TSHRL3MBTL1PPARGALDH1A1 | |
| SCHEMBL25393523 | 0.67 | EPHX2 (0.48) | EPHX2PPARGALDH1A1MEN1KMT2A | |
| SCHEMBL28700042 | 0.67 | FEN1 (0.43) | EPHX2 | |
| SCHEMBL25393273 | 0.66 | EPHX2 (0.50) | EPHX2ALDH1A1CNR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107787322-B | Tricyclic compounds and their use as phosphodiesterase inhibitors | 辉瑞大药厂 | 2023-07-07 | — | — | CN | disclosed |