SCHEMBL29033174

SCHEMBL29033174

CC1(C)C(=O)OC1CCCCOCc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.43
ALDH1A1 P00352 2/20 0.42
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
KMT2A Q03164 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
LMNA P02545 1/20 0.40
EPHX2 P34913 2/20 0.39
KCNA3 P22001 2/20 0.37
KCNA5 P22460 2/20 0.37
SOAT1 P35610 1/20 0.37
TSHR P16473 1/20 0.37
PTPN1 P18031 1/20 0.36
CDC25B P30305 1/20 0.36
HRH4 Q9H3N8 1/20 0.35
HRH3 Q9Y5N1 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29033172 0.96 NAAA (0.44) NAAAALDH1A1MEN1MAPTKMT2A
SCHEMBL12903277 0.73 LMNA (0.49) NAAAMEN1KMT2AL3MBTL1TDP1
SCHEMBL1351486 0.73 CTRB1 (0.41) TSHR
SCHEMBL8876347 0.72 TDP1 (0.43) NAAAALDH1A1MEN1MAPTKMT2A
SCHEMBL2640223 0.72 TSHR (0.70) NAAAL3MBTL1TDP1EPHX2KCNA3
SCHEMBL23533386 0.71 EPHX2 (0.48) ALDH1A1MEN1KMT2AL3MBTL1TDP1
SCHEMBL28827303 0.71 EPHX2 (0.48) ALDH1A1MEN1KMT2AL3MBTL1TDP1
SCHEMBL21804589 0.71 NAAA (0.44) NAAAALDH1A1MEN1MAPTKMT2A
SCHEMBL2916335 0.70 FASN (0.61) NAAAL3MBTL1TDP1LMNAEPHX2
SCHEMBL18227609 0.70 HTR7 (0.51) NAAAALDH1A1MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116410086-A Method for preparing isobutyric acid derivative 苏州特瑞药业股份有限公司 2023-07-11 CN disclosed