SCHEMBL29033172

SCHEMBL29033172

CC1(C)C(=O)OC1CCCOCc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.44
ALDH1A1 P00352 3/20 0.43
LMNA P02545 1/20 0.41
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TSHR P16473 1/20 0.38
EPHX2 P34913 1/20 0.38
PTPN1 P18031 1/20 0.37
CDC25B P30305 1/20 0.37
KCNA3 P22001 2/20 0.36
KCNA5 P22460 2/20 0.36
SOAT1 P35610 1/20 0.35
HRH4 Q9H3N8 1/20 0.35
HRH3 Q9Y5N1 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35
CTSV O60911 1/20 0.35
CTSL P07711 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29033174 0.96 NAAA (0.43) NAAAALDH1A1LMNAMEN1MAPT
SCHEMBL21804589 0.75 NAAA (0.44) NAAAALDH1A1LMNAMEN1MAPT
SCHEMBL1351486 0.74 CTRB1 (0.41) TSHR
SCHEMBL18227499 0.73 HTR7 (0.57)
SCHEMBL18227593 0.71 HTR7 (0.51) NAAAALDH1A1LMNAMEN1KMT2A
SCHEMBL18227591 0.71 HTR7 (0.51) NAAAALDH1A1LMNAMEN1KMT2A
SCHEMBL18227609 0.71 HTR7 (0.51) NAAAALDH1A1LMNAMEN1KMT2A
SCHEMBL8621469 0.69 TSHR (0.70) NAAATDP1L3MBTL1TSHRHRH4
SCHEMBL2640223 0.69 TSHR (0.70) NAAATDP1L3MBTL1TSHREPHX2
SCHEMBL23533293 0.69 L3MBTL1 (0.40) ALDH1A1TDP1L3MBTL1TSHREPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116410086-A Method for preparing isobutyric acid derivative 苏州特瑞药业股份有限公司 2023-07-11 CN disclosed