Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 13/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2903457 | 1.00 | CCR2 (0.51) | CCR2MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL2903225 | 0.95 | ALDH1A1 (0.54) | CCR2MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL2903222 | 0.95 | ALDH1A1 (0.54) | CCR2MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL2904336 | 0.88 | MEN1 (0.51) | MEN1ALDH1A1LMNAKMT2ADRD2 | |
| SCHEMBL2904334 | 0.88 | MEN1 (0.51) | MEN1ALDH1A1LMNAKMT2ADRD2 | |
| SCHEMBL2902775 | 0.86 | ITGB2 (0.51) | MEN1ALDH1A1LMNAKMT2AACHE | |
| SCHEMBL2902774 | 0.86 | ITGB2 (0.51) | MEN1ALDH1A1LMNAKMT2AACHE | |
| SCHEMBL2905214 | 0.85 | LMNA (0.73) | CCR2MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL2905217 | 0.85 | LMNA (0.73) | CCR2MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL2904465 | 0.85 | ALDH1A1 (0.51) | MEN1ALDH1A1LMNAKMT2AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010506-B1 | DIAZEPAN DERIVATIVES MODULATORS OF CHEMOKINE RECEPTORS | HOFFMANN LA ROCHE (CH) | 2010-08-04 | — | — | EP | disclosed |