Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.51 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.51 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2905214 | 1.00 | LMNA (0.73) | LMNAALDH1A1MEN1KMT2AGAA | |
| SCHEMBL2903225 | 0.88 | ALDH1A1 (0.54) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL2903222 | 0.88 | ALDH1A1 (0.54) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL2904334 | 0.85 | MEN1 (0.51) | LMNAALDH1A1MEN1KMT2AGAA | |
| SCHEMBL2904336 | 0.85 | MEN1 (0.51) | LMNAALDH1A1MEN1KMT2AGAA | |
| SCHEMBL2903457 | 0.85 | CCR2 (0.51) | LMNAALDH1A1MEN1KMT2AACHE | |
| SCHEMBL2903456 | 0.85 | CCR2 (0.51) | LMNAALDH1A1MEN1KMT2AACHE | |
| SCHEMBL2904467 | 0.85 | ALDH1A1 (0.51) | LMNAALDH1A1MEN1KMT2AGAA | |
| SCHEMBL2904465 | 0.85 | ALDH1A1 (0.51) | LMNAALDH1A1MEN1KMT2AGAA | |
| SCHEMBL2902775 | 0.84 | ITGB2 (0.51) | LMNAALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010506-B1 | DIAZEPAN DERIVATIVES MODULATORS OF CHEMOKINE RECEPTORS | HOFFMANN LA ROCHE (CH) | 2010-08-04 | — | — | EP | disclosed |