Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | EP300 | Q09472 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3756565 | 0.89 | POLB (0.57) | ALDH1A1SMN1; SMN2MAPTHPGDTDP1 | |
| SCHEMBL2903213 | 0.84 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MAPTHPGDTDP1 | |
| SCHEMBL21786249 | 0.83 | LMNA (0.60) | ALDH1A1SMN1; SMN2MAPTTDP1POLB | |
| SCHEMBL7674914 | 0.78 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2GAANPSR1MEN1 | |
| SCHEMBL16127963 | 0.78 | ALDH1A1 (0.69) | ALDH1A1SLC16A3HPGDTDP1POLB | |
| SCHEMBL2897478 | 0.78 | NPC1 (0.50) | ALDH1A1SMN1; SMN2MAPTHPGDTDP1 | |
| SCHEMBL3050268 | 0.75 | MCOLN3 (0.68) | ALDH1A1SMN1; SMN2SLC16A3MAPTTDP1 | |
| SCHEMBL3043992 | 0.75 | PTPN1 (0.63) | SLC16A3MAPTPOLBGAAGFER | |
| SCHEMBL3047861 | 0.75 | MEN1 (0.66) | ALDH1A1SLC16A3STAT3EP300PTPN1 | |
| SCHEMBL3041146 | 0.74 | BDKRB1 (0.70) | ALDH1A1SLC16A3HPGDPOLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298299-A1 | NON-PEPTIDE DERIVATIVES AS BRADYKININ B1 ANTAGONISTS | RICHTER GEDEON NYRT. (HU) | 2010-11-25 | — | — | US | disclosed |
| EP-2215055-A1 | NEW NON-PEPTIDE DERIVATIVES AS BRADYKININ B1 ANTAGONISTS | Richter Gedeon Nyrt. (HU) | 2010-08-11 | — | — | EP | disclosed |
| WO-2009053763-A1 | NEW NON-PEPTIDE DERIVATIVES AS BRADYKININ BL ANTAGONISTS | RICHTER GEDEON NYRT. (HU) | 2009-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298299-A1 | NON-PEPTIDE DERIVATIVES AS BRADYKININ B1 ANTAGONISTS | BDKRB1, BDKRB2, NPBWR1 | ALDH1A1 4439/4885SMN1; SMN2 4628/4885SLC16A3 2969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.