Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17347353 | 0.83 | TSHR (0.55) | TSHRLMNAALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL177151 | 0.77 | TSHR (0.70) | TSHRLMNAALDH1A1ALOX15TRPV1 | |
| SCHEMBL2903520 | 0.77 | TSHR (0.70) | TSHRLMNAALDH1A1ALOX15TRPV1 | |
| SCHEMBL13815837 | 0.74 | ALDH1A1 (0.65) | TSHRLMNAALDH1A1ALOX15ACHE | |
| SCHEMBL19334362 | 0.73 | ACHE (0.63) | TSHRLMNAALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL13815840 | 0.73 | TSHR (0.77) | TSHRLMNAALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL12707526 | 0.73 | ALDH1A1 (0.63) | TSHRLMNAALDH1A1ALOX15 | |
| Acetic Acid SCHEMBL31622747 | 0.72 | ALDH1A1 (0.59) | TSHRLMNAALDH1A1ALOX15TRPV1 | |
| Acetic Acid SCHEMBL27720602 | 0.72 | ALDH1A1 (0.59) | TSHRLMNAALDH1A1ALOX15TRPV1 | |
| Formaldehyde SCHEMBL22288207 | 0.72 | FAAH (0.44) | LMNACYP1A2CYP2D6CYP2C19THPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1253470-B1 | Radiation-sensitive resin composition | JSR CORP (JP) | 2010-06-16 | — | — | EP | disclosed |