SCHEMBL505810

SCHEMBL505810

COc1ccc(C(=O)CO)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 2/20 0.68
HDAC4 P56524 2/20 0.68
HDAC1 Q13547 2/20 0.68
HDAC7 Q8WUI4 2/20 0.68
HDAC2 Q92769 2/20 0.68
HDAC10 Q969S8 2/20 0.68
HDAC11 Q96DB2 2/20 0.68
HDAC8 Q9BY41 2/20 0.68
HDAC6 Q9UBN7 2/20 0.68
HDAC9 Q9UKV0 2/20 0.68
HDAC5 Q9UQL6 2/20 0.68
GSK3B P49841 1/20 0.68
CES2 O00748 1/20 0.61
CES1 P23141 1/20 0.61
MAPT P10636 1/20 0.61
PDE4B Q07343 1/20 0.59
CA1 P00915 5/20 0.59
CA2 P00918 5/20 0.59
NPC1 O15118 2/20 0.58
RAB9A P51151 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3540405 0.86 SMN1; SMN2 (0.71) MAPTNPC1RAB9AALDH1A1PARP10
SCHEMBL153386 0.84 ALDH1A1 (0.76) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL16552644 0.84 MMP1 (0.76) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL28029377 0.84 HDAC8 (0.65) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL2633872 0.83 MAPT (0.68) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL459470 0.83 KMT2A (0.70) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL1267569 0.83 HDAC3 (0.68) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL4082864 0.81 PDE4B (0.86) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL5806919 0.81 HDAC3 (0.66) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL182867 0.81 HDAC3 (0.66) HDAC3HDAC4HDAC1HDAC7HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 632 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116606312-B Near infrared two-region photosensitizer based on aza-boron dipyrrole, preparation method and application 西北工业大学 2025-05-20 CN claimed
CN-118879135-B Strong-adhesion and high-weather-resistance water-based fluorocarbon paint for GRPU base materials and preparation method thereof 上海颜钛实业有限公司 2025-04-15 CN claimed
CN-117442600-B Atomized essence additive, atomized essence and aerosol generating device 深圳昱朋科技有限公司 2024-06-18 CN claimed
CN-117442600-A Atomized essence additive, atomized essence and aerosol generating device 深圳昱朋科技有限公司 2024-01-26 CN claimed
CN-116999417-A Liquid preparation containing paeonol and apocynin AKL研究发展有限公司 2023-11-07 CN claimed
CN-114751870-B 2- (isoxazole-5-yl) phenyl-3, 4-dihydroxybenzoate and derivative thereof, and synthetic method and application thereof 贵州医科大学 2023-10-20 CN claimed
US-20230330017-A1 LIQUID FORMULATION COMPRISING PAEONOL AND APOCYNIN AKL RES & DEVELOPMENT LTD (GB) 2023-10-19 US claimed
CN-116813501-A Chalcone fluorescent probe, preparation method thereof and detection method for H 2 Application in S 广东省科学院化工研究所 2023-09-29 CN claimed
CN-116606312-A Near infrared two-region photosensitizer based on aza-boron dipyrrole, preparation method and application 西北工业大学 2023-08-18 CN claimed
CN-113999218-B Flavonol compound, preparation method and application thereof in detection of biological mercaptan 德州学院 2023-06-09 CN claimed
US-20070231318-A1 BENZOFURAN COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES SAHA ASHIS K 2007-10-04 US claimed
US-7265152-B2 Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis C viral infections and associated diseases VIROPHARMA INCORPORATED (US) 2007-09-04 US claimed
EP-1581207-A4 BENZOFURAN COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES VIROPHARMA INC (US) 2007-07-25 EP claimed
EP-1746888-A2 COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES Viropharma Incorporated (US) 2007-01-31 EP claimed
JP-2006510736-A 2006-03-30 JP claimed
WO-2005112640-A2 COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES VIROPHARMA INCORPORATED (US) 2005-12-01 WO claimed
EP-1581207-A2 BENZOFURAN COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES Viropharma Incorporated (US) 2005-10-05 EP claimed
US-20040162318-A1 Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis C viral infections and associated diseases VIROPHARMA INCORPORATED 2004-08-19 US claimed
WO-2004041201-A2 BENZOFURAN COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES VIROPHARMA INCORPORATED (US) 2004-05-21 WO claimed
WO-2004005280-A1 NOVEL QUINOLINIC COMPOUNDS SHOWING A FEATURE OF EXCITED-STATE INTRAMOLECULAR PROTON TRANSFER (ESIPT) DONGWOO FINE-CHEM CO., LTD. (KR) 2004-01-15 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070231318-A1 BENZOFURAN COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES BBOX1, HAVCR2, CYP2E1 HDAC3 896/4885HDAC4 858/4885HDAC1 1096/4885
US-20230330017-A1 LIQUID FORMULATION COMPRISING PAEONOL AND APOCYNIN LPL, PNLIP, LPO HDAC3 3155/4885HDAC4 2719/4885HDAC1 1237/4885
US-20040162318-A1 Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis C viral infections and associated diseases BBOX1, HAVCR2, CYP2E1 HDAC3 896/4885HDAC4 858/4885HDAC1 1096/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.