Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 4/20 | 0.96 |
| ▸ | PLAU | P00749 | 2/20 | 0.96 |
| ▸ | METAP2 | P50579 | 2/20 | 0.57 |
| ▸ | BACE1 | P56817 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | PIM1 | P11309 | 1/20 | 0.55 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL361523 | 0.98 | NCF1 (1.00) | NCF1PLAUMETAP2BACE1ALDH1A1 | |
| SCHEMBL30457846 | 0.96 | NCF1 (0.96) | NCF1PLAUMETAP2BACE1ALDH1A1 | |
| SCHEMBL29015130 | 0.96 | NCF1 (0.96) | NCF1PLAUMETAP2BACE1ALDH1A1 | |
| SCHEMBL29040600 | 0.96 | NCF1 (0.96) | NCF1PLAUMETAP2BACE1ALDH1A1 | |
| SCHEMBL437684 | 0.77 | PLAU (0.64) | NCF1PLAUMETAP2ALDH1A1CYP1A2 | |
| SCHEMBL31424217 | 0.77 | PLAU (0.64) | NCF1PLAUMETAP2ALDH1A1CYP1A2 | |
| SCHEMBL21975961 | 0.76 | NCF1 (0.63) | NCF1PLAUBACE1MCHR1 | |
| SCHEMBL21767732 | 0.76 | METAP2 (0.63) | NCF1PLAUMETAP2ALDH1A1CYP1A2 | |
| SCHEMBL30082244 | 0.76 | METAP2 (0.63) | NCF1PLAUMETAP2ALDH1A1CYP1A2 | |
| SCHEMBL672744 | 0.76 | METAP2 (0.63) | NCF1PLAUMETAP2ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444324-A | Application of organic lead salt, composition and preparation method thereof | 中国科学院上海有机化学研究所 | 2023-07-18 | — | — | CN | disclosed |